Table 3. The stability of GA liposomes (GA-LP and Gal-GA-LP).
Condition | Leakage rate (%)±S.D. | ||
---|---|---|---|
GA-LP | Gal-GA-LP | ||
25°C±2°C, 60%±5% 2 weeks | 2.39±0.49 | 2.00±0.20 | |
25°C±2°C | 1stmonth | 1.53±0.54 | 1.41±0.55 |
2nd month | 3.96±0.49 | 3.20±0.53 | |
3rd month | 6.08±0.62 | 5.45±0.41 | |
4°C±1°C | 3rd month | 3.28±0.27 | 2.75±0.73 |
6th month | 4.53±0.87 | 4.51±0.90 |
Notes: Data shown represent the mean ± S.D.
Abbreviations: S.D., standard deviation; GA, glycyrrhetinic acid; GA-LP, glycyrrhetinic acid liposomes; Gal-GA-LP, glycyrrhetinic acid liposomes modified with liver-targeting ligand of galactosylated derivative.