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. 2017 Oct 27;8(60):102067–102077. doi: 10.18632/oncotarget.22155

Figure 3. Effects of intravenously transplanted NSCs on migration and survival in ischemic stroke rats.

Figure 3

(A) The distribution of transplanted NSCs in the infarct region. Cell Tacker CM-DiI-positive cells were shown in red. The cells were mainly limited to the infarcted areas, although some were sparsely observed throughout the affected hemisphere (Scale bar: 200 μm). (B) The number of CM-DiI-positive cells was measured in the contralateral and infarction. (C) The expression of bFGF in the infarct region at 28 days after MCAO. bFGF promotes NSCs’ migration and maintains the survival of cells in the infarcted lesion. CM-DiI-positive cells were shown in red; bFGF-immunopositive cells were shown in green (scale bar: 50 μm). (D) The number of bFGF-positive cells was measured in the infarct area. CM-DiI and bFGF-positive co-labeled cells representing the exogenous NSCs; bFGF-positive single cells representing the endogenous cells. The error bars represent the means ± SEM, n = 6 each group; *P < 0.05.