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. 2017 Oct 31;8(60):102119–102133. doi: 10.18632/oncotarget.22183

Figure 5. SiTET1 promotes the motility and invasion of BC cells.

Figure 5

(a) The effect of downregulating TET1 on cell proliferation was determined using the CCK-8 assay. (b) Colony formation assays for MDA-MB-231 and MCF-7 cells transfected with siTET1. The number of colonies were scored in ten randomly selected fields. Each bar represents the mean of three independent experiments. (c) Data from the wound healing assay for MDA-MB-231 and MCF-7 cells transfected with siTET1. Bars represent the migration rate of invading cells after transfection with siTET1. (d) Western blot was performed to detect E-cadherin and Vimentin expression in MDA-MB-231 and MCF-7 cells transfected with siTET1. Data are expressed as the means ± S.E.M; n = 3. *P < 0.05; **P < 0.01.