. 2017 Sep 19;8(60):102301–102309. doi: 10.18632/oncotarget.21084

Table 1. The baseline characteristics of all qualified studies in this meta-analysis.

Name	Year	Country	Ethnicity	Control Source	Genotype method	Language	Case				Control				HWE	Score
Name	Year	Country	Ethnicity	Control Source	Genotype method	Language	CC	CT	TT	All	CC	CT	TT	All	HWE	Score
Wiencke	1997	USA	Caucasian	PB	PCR	English	29	32		61	52	109		161	—	10
Wiencke	1997	USA	African-American	PB	PCR	English	77	39		116	83	53		136	—	10
Chen	1999	USA (Hawaii)	Asian	PB	PCR-RFLP	English	54	48	7	109	64	78	25	167	0.877	10
Chen	1999	USA (Hawaii)	Caucasian	PB	PCR-RFLP	English	81	49	5	135	105	62	4	171	0.137	10
Chen	1999	USA (Hawaii)	Hawaiian	PB	PCR-RFLP	English	61	18	4	83	60	39	3	102	0.258	10
Lin	2000	China	Asian	HB	PCR-RFLP	Chinese	12	63	20	95	41	73	22	136	0.268	3
Yin	2001	China	Asian	HB	PCR-CTPP	English	28	39	17	84	26	41	17	84	0.909	6
Xu	2001	USA	Caucasian	HB	PCR-RFLP	English	513	246	21	780	715	341	40	1096	0.933	6
Xu	2001	USA	Mixed	HB	PCR-RFLP	English	18	14	2	34	20	6	1	27	0.534	7
Lewis	2001	UK	Caucasian	HB	PCR	English	56	24	2	82	111	32	2	145	0.858	4
Benhamou	2001	France	Caucasian	HB	PCR-RFLP	English	85	55	10	150	105	62	5	172	0.243	10
Sunaga	2002	Japan	Asian	HB	PCR-RFLP	English	83	93	22	198	52	77	23	152	0.526	6
Hamajima	2002	Japan	Asian	HB	PCR-CTPP	English	87	71	34	192	240	286	114	640	0.076	6
Lin	2003	China	Asian	HB	PCR	English	57	141		198	95	237		332	—	9
Yin	2003	China	Asian	PB	PCR	Chinese	26	41	17	84	28	39	17	84	0.613	4
Lan	2004	China	Asian	PB	PCR	English	37	57	25	119	32	54	23	109	0.980	8
Liang	2004	China	Asian	HB	PCR-RFLP	Chinese	37	79	36	152	53	71	28	152	0.624	7
Alexandrie	2004	Sweden	Caucasian	HB	AS-PCR	English	345	168	11	524	368	153	9	530	0.124	7
Sorensen	2005	Denmark	Caucasian	PB	TaqMan	English	162	83	9	254	176	80	11	267	0.618	10
Saldivar	2005	USA	Caucasian	PB	PCR-RFLP	English	454	205	24	683	480	186	17	683	0.839	11
Saldivar	2005	USA	Hispanics	PB	PCR-RFLP	English	15	17	4	36	15	14	7	36	0.275	8
Saldivar	2005	USA	African-American	PB	PCR-RFLP	English	67	33	7	107	69	35	3	107	0.563	9
Skuladottir	2005	Denmark	Caucasians	Mixed	PCR-RFLP	English	108	45		153	227	119		346	—	6
Chan	2005	China	Asian	HB	PCR-RFLP	English	25	37	13	75	45	83	34	162	0.708	5
Bock	2005	USA	Caucasian	PB	TaqMan	English	93	37		130	87	57		144	—	7
Bock	2005	USA	African-American	PB	TaqMan	English	21	10		31	21	8		29	—	7
Lawson	2005	Finland	Caucasian	PB	PCR	English	244	109		353	243	117		360	—	10
Demirkan	2005	Turkey	Caucasian	PB	PCR	English	47	34	7	88	80	34	3	117	0.785	4
Yang	2007	Korea	Asian	HB	TaqMan	English	110	158	46	314	120	166	61	347	0.784	10
Eom	2009	Korea	Asian	HB	PCR-RFLP	English	122	265		387	148	239		387	—	9
Cote	2009	USA	Caucasian	PB	TaqMan	English	271	97	19	387	271	119	15	405	0.668	11
Cote	2009	USA	African-American	PB	TaqMan	English	77	32	4	113	79	36	6	121	0.478	10
Su	2009	China	Asian	PB	PCR-RFLP	Chinese	102	199	95	396	139	244	82	465	0.158	8
Timofeeva	2010	Germany	Caucasian	PB	MALDI-TOF MS	English	429	188		617	856	411		1267	-	10
Guo	2012	China	Asian	HB	PCR-LDR	English	187	327	168	682	171	282	144	597	0.192	8
Tian	2014	China	Asian	HB	PCR	English	88	171	132	391	215	307	141	663	0.109	10
Masroor	2015	India	Asian	HB	AS-PCR	English	45	48	7	100	71	26	3	100	0.743	6

HB, hospital based; PB, population based; PCR, polymerase chain reaction; AS-PCR, Allele specific-PCR; PCR-RFLP, PCR-restriction fragment length polymorphism; MALDI-TOF MS, Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry; HWE, Hardy-Weinberg equilibrium.