Table 2. ALDH2 (rs671) polymorphisms genotype distribution and allele frequency in cases and controls.
First author | Year | Genotype(N) | MAF | HWE | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Case | Control | Case | Control | ||||||||||||
Total | GG | GA | AA | Total | GG | GA | AA | G | A | G | A | ||||
Zhao et al. [18] | 2014 | 308 | 194 | 106 | 8 | 308 | 194 | 100 | 14 | 494 | 122 | 488 | 128 | 0.21 | 0.81 |
Li et al. [19] | 2009 | 192 | 101 | 76 | 15 | 191 | 114 | 66 | 11 | 278 | 106 | 294 | 88 | 0.48 | 0.72 |
Zhou et al. [15] | 2010 | 201 | 99 | 91 | 11 | 199 | 97 | 91 | 11 | 289 | 113 | 285 | 113 | 0.28 | 0.08 |
Yuan et al. [20] | 2016 | 161 | 104 | 50 | 7 | 161 | 99 | 60 | 2 | 258 | 64 | 258 | 64 | 0.19 | 0.03 |
Hidaka et al. [21] | 2015 | 457 | 287 | 149 | 21 | 457 | 292 | 150 | 15 | 723 | 191 | 734 | 180 | 0.20 | 0.42 |
Yang et al. [22] | 2016 | 450 | 304 | 141 | 5 | 1050 | 736 | 292 | 22 | 749 | 151 | 1764 | 336 | 0.23 | 0.26 |
Cao et al. [23] | 2010 | 382 | 196 | 161 | 25 | 382 | 206 | 155 | 21 | 553 | 211 | 567 | 197 | 0.26 | 0.24 |
Chen et al. [24] | 2016 | 246 | 133 | 95 | 18 | 274 | 163 | 101 | 10 | 361 | 131 | 427 | 121 | 0.22 | 0.24 |
Zhang et al. [25] | 2017 | 2686 | 1995 | 643 | 48 | 3675 | 2663 | 941 | 71 | 4633 | 739 | 6267 | 1083 | 0.15 | 0.25 |
Matsuo et al. [10] | 2013 | 696 | 310 | 323 | 63 | 1372 | 683 | 580 | 109 | 943 | 449 | 1946 | 798 | 0.29 | 0.36 |
Chang et al. [26] | 2014 | 196 | 108 | 76 | 12 | 393 | 213 | 160 | 20 | 292 | 100 | 586 | 200 | 0.25 | 0.15 |
Shin et al. [9] | 2011 | 445 | 291 | 141 | 13 | 370 | 250 | 102 | 18 | 723 | 167 | 602 | 138 | 0.19 | 0.08 |
MAF: minor allele frequency; HWE: Hardy-Weinberg equilibrium.