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. 2017 Oct 19;8(60):102401–102412. doi: 10.18632/oncotarget.22060

Table 3. Meta-analysis results.

Genetic model Category OR (95% CI) P Bon FDR Heterogeneity Begg's test Egger test
I2 P P P
AA VS GG Overall 1.101 [0.924; 1.313] 0.282 1.000 0.461 23.2% 0.215 0.837 0.872
China 1.110 [0.879; 1.403] 0.380 1.000 0.693 20.4% 0.267
Japan 1.303 [0.963; 1.763] 0.087 0.435 0.109 0.0% 0.773
Korea 0.592 [0.329; 1.064] 0.080 0.400 0.155 0.0% 0.847
HB 0.592 [0.329; 1.064] 0.926 1.000 0.926 52.4% 0.062
PB 0.592 [0.329; 1.064] 0.074 0.370 0.220 0.0% 0.845
GA VS GG Overall 1.030 [0.959; 1.106] 0.423 1.000 0.461 12.7% 0.321 0.537 0.240
China 0.965 [0.883; 1.055] 0.431 1.000 0.693 0.0% 0.611
Japan 1.152 [0.985; 1.350] 0.076 0.380 0.109 20.8% 0.261
Korea 1.176 [0.973; 1.422] 0.093 0.465 0.155 0.0% 0.937
HB 1.033 [0.952; 1.122] 0.435 1.000 0.926 48.6% 0.083
PB 1.019 [0.882; 1.176] 0.801 1.000 0.801 0.0% 0.726
Allele model Overall 1.031 [0.972; 1.093] 0.310 1.000 0.461 10.9% 0.339 0.945 0.185
China 0.991 [0.921; 1.067] 0.815 1.000 0.815 14.9% 0.313
Japan 1.138 [1.010; 1.281] 0.034 0.170 0.100 0.0% 0.582
Korea 1.037 [0.883; 1.218] 0.659 1.000 0.659 0.0% 0.768
HB 1.016 [0.949; 1.088] 0.647 1.000 0.926 49.9% 0.076
PB 1.072 [0.957; 1.200] 0.229 1.000 0.381 0.0% 0.884
Recessive model Overall 1.067 [0.898; 1.268] 0.461 1.000 0.461 20.6% 0.241 0.745 0.813
China 1.107 [0.878; 1.395] 0.389 1.000 0.693 15.6% 0.308
Japan 1.200 [0.897; 1.607] 0.220 1.000 0.220 0.0% 0.587
Korea 0.563 [0.314; 1.008] 0.053 0.265 0.155 0.0% 0.854
HB 0.973 [0.790; 1.198] 0.799 1.000 0.926 47.6% 0.089
PB 1.312 [0.960; 1.793] 0.088 0.440 0.220 0.0% 0.825
Dominant model Overall 1.033 [0.963; 1.107] 0.365 1.000 0.461 13.8% 0.309 0.537 0.163
China 0.974 [0.894; 1.062] 0.554 1.000 0.693 0.0% 0.465
Japan 1.172 [1.008; 1.364] 0.040 0.200 0.100 0.0% 0.325
Korea 1.116 [0.928; 1.342] 0.365 1.000 0.456 0.0% 0.914
HB 1.026 [0.947; 1.112] 0.526 1.000 0.926 51.0% 0.070
PB 1.052 [0.916; 1.208] 0.476 1.000 0.595 0.0% 0.781

OR: odds ratio; 95% CI: 95% confidence interval; Bon: P-value in Bonferroni testing; FDR: false discovery rate.