Table 3. Meta-analysis results.
Genetic model | Category | OR (95% CI) | P | Bon | FDR | Heterogeneity | Begg's test | Egger test | |
---|---|---|---|---|---|---|---|---|---|
I2 | P | P | P | ||||||
AA VS GG | Overall | 1.101 [0.924; 1.313] | 0.282 | 1.000 | 0.461 | 23.2% | 0.215 | 0.837 | 0.872 |
China | 1.110 [0.879; 1.403] | 0.380 | 1.000 | 0.693 | 20.4% | 0.267 | |||
Japan | 1.303 [0.963; 1.763] | 0.087 | 0.435 | 0.109 | 0.0% | 0.773 | |||
Korea | 0.592 [0.329; 1.064] | 0.080 | 0.400 | 0.155 | 0.0% | 0.847 | |||
HB | 0.592 [0.329; 1.064] | 0.926 | 1.000 | 0.926 | 52.4% | 0.062 | |||
PB | 0.592 [0.329; 1.064] | 0.074 | 0.370 | 0.220 | 0.0% | 0.845 | |||
GA VS GG | Overall | 1.030 [0.959; 1.106] | 0.423 | 1.000 | 0.461 | 12.7% | 0.321 | 0.537 | 0.240 |
China | 0.965 [0.883; 1.055] | 0.431 | 1.000 | 0.693 | 0.0% | 0.611 | |||
Japan | 1.152 [0.985; 1.350] | 0.076 | 0.380 | 0.109 | 20.8% | 0.261 | |||
Korea | 1.176 [0.973; 1.422] | 0.093 | 0.465 | 0.155 | 0.0% | 0.937 | |||
HB | 1.033 [0.952; 1.122] | 0.435 | 1.000 | 0.926 | 48.6% | 0.083 | |||
PB | 1.019 [0.882; 1.176] | 0.801 | 1.000 | 0.801 | 0.0% | 0.726 | |||
Allele model | Overall | 1.031 [0.972; 1.093] | 0.310 | 1.000 | 0.461 | 10.9% | 0.339 | 0.945 | 0.185 |
China | 0.991 [0.921; 1.067] | 0.815 | 1.000 | 0.815 | 14.9% | 0.313 | |||
Japan | 1.138 [1.010; 1.281] | 0.034 | 0.170 | 0.100 | 0.0% | 0.582 | |||
Korea | 1.037 [0.883; 1.218] | 0.659 | 1.000 | 0.659 | 0.0% | 0.768 | |||
HB | 1.016 [0.949; 1.088] | 0.647 | 1.000 | 0.926 | 49.9% | 0.076 | |||
PB | 1.072 [0.957; 1.200] | 0.229 | 1.000 | 0.381 | 0.0% | 0.884 | |||
Recessive model | Overall | 1.067 [0.898; 1.268] | 0.461 | 1.000 | 0.461 | 20.6% | 0.241 | 0.745 | 0.813 |
China | 1.107 [0.878; 1.395] | 0.389 | 1.000 | 0.693 | 15.6% | 0.308 | |||
Japan | 1.200 [0.897; 1.607] | 0.220 | 1.000 | 0.220 | 0.0% | 0.587 | |||
Korea | 0.563 [0.314; 1.008] | 0.053 | 0.265 | 0.155 | 0.0% | 0.854 | |||
HB | 0.973 [0.790; 1.198] | 0.799 | 1.000 | 0.926 | 47.6% | 0.089 | |||
PB | 1.312 [0.960; 1.793] | 0.088 | 0.440 | 0.220 | 0.0% | 0.825 | |||
Dominant model | Overall | 1.033 [0.963; 1.107] | 0.365 | 1.000 | 0.461 | 13.8% | 0.309 | 0.537 | 0.163 |
China | 0.974 [0.894; 1.062] | 0.554 | 1.000 | 0.693 | 0.0% | 0.465 | |||
Japan | 1.172 [1.008; 1.364] | 0.040 | 0.200 | 0.100 | 0.0% | 0.325 | |||
Korea | 1.116 [0.928; 1.342] | 0.365 | 1.000 | 0.456 | 0.0% | 0.914 | |||
HB | 1.026 [0.947; 1.112] | 0.526 | 1.000 | 0.926 | 51.0% | 0.070 | |||
PB | 1.052 [0.916; 1.208] | 0.476 | 1.000 | 0.595 | 0.0% | 0.781 |
OR: odds ratio; 95% CI: 95% confidence interval; Bon: P-value in Bonferroni testing; FDR: false discovery rate.