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. 2017 Oct 19;8(60):102401–102412. doi: 10.18632/oncotarget.22060

Table 4. Association between ALDH2 rs671 G>A polymorphism and sex, smoking status and drinking status of the gastric cancer patients based on dominant models.

Subgroup analyses Dominant model: GA + AA vs. GG
Heterogeneity
OR 95% CI P value I2 PHet Effects model No. of studies
Sex
Male 1.049 0.942–1.168 0.385 93.9% <0.001 R 2
Female 1.053 0.905–1.224 0.506 0.0% 0.980 F 2
Smoking status
Smoker 1.212 0.851–1.728 0.286 0.0% 0.612 F 2
Nonsmoker 0.599 0.400–0.897 0.080 43.2% 0.184 F 2
Drinking status
Drinker 1.421 1.211–1.667 < 0.001 22.5% 0.257 F 7
Nondrinker 1.031 0.879–1.209 0.707 40.8% 0.119 F 7

F: fixed effects model; R: random effects model.