Table 4. Association between ALDH2 rs671 G>A polymorphism and sex, smoking status and drinking status of the gastric cancer patients based on dominant models.
Subgroup analyses | Dominant model: GA + AA vs. GG | ||||||
---|---|---|---|---|---|---|---|
Heterogeneity | |||||||
OR | 95% CI | P value | I2 | PHet | Effects model | No. of studies | |
Sex | |||||||
Male | 1.049 | 0.942–1.168 | 0.385 | 93.9% | <0.001 | R | 2 |
Female | 1.053 | 0.905–1.224 | 0.506 | 0.0% | 0.980 | F | 2 |
Smoking status | |||||||
Smoker | 1.212 | 0.851–1.728 | 0.286 | 0.0% | 0.612 | F | 2 |
Nonsmoker | 0.599 | 0.400–0.897 | 0.080 | 43.2% | 0.184 | F | 2 |
Drinking status | |||||||
Drinker | 1.421 | 1.211–1.667 | < 0.001 | 22.5% | 0.257 | F | 7 |
Nondrinker | 1.031 | 0.879–1.209 | 0.707 | 40.8% | 0.119 | F | 7 |
F: fixed effects model; R: random effects model.