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. 2017 Oct 9;8(60):102550–102558. doi: 10.18632/oncotarget.21684

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Copyright: © 2017 Wu et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License 3.0 (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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(A) Prevalence of DKD in four risk groups stratified by risk score in the development population. (B) Receiver operating curve (ROC) for the development, validation 1 and validation 2 cohorts. The AUC of development, validation1 and validation 2 were 0.713(0.692–0.734), 0.720 (0.696–0.744) and 0.696(0.632–0.760), respectively. Difference between the curves for DKD was not significant (U = 0.43, P = 0.667). (C) Kaplan-Meier curve of DKD end point for each risk group. Moderate group: HR 2.04 (95% confidence interval [CI] 0.76 to 5.46), P = 0.23. High group: HR 3.97 (95% CI 1.90 to 8.33), P = 0.01. Very high group: Hazard ratio (HR) 11.37 (95% CI 4.76 to 27.19), P < 0.0001. Low risk group: Reference.