Table I.

Identification of CD11c+ and related B cells in mice and humans

Condition	References	Comments
Healthy humans	[19]	CD11c+ detected on activated B cells
Ehrlichial infection	[1, 48]	CD11c+ identified on spleen plasmablasts and IgM memory cells
Aged humans and SLE patients	[35] [36]	CD11c+ T-bet+ B cells (ABCs); autoreactive Abs detected in aged mice
Hairy Cell Leukemia (HCL) and variant	[21, 91, 92]	CD11c expression on IgM⁺ lymphoma cells; BRAF mutation is associated with cell growth
Viral infections	[37] [38]	CD11c⁺ T-bet⁺ B cells detected early in response to infections
Healthy humans	[22] [23]	CD11c expression detected on FcRL4+ non-germinal center memory B cells in tonsils
Healthy humans	[24]	CD11c expression detected on FcRL5 IgM⁺ CD21^low tissue-like memory B cells
Healthy humans	[93]	CD11c⁺ expression on IgM⁺ memory cells in blood
Hepatitis C, B infection	[33] [31], [94] [25]	Accumulation of IgM⁺ CD11c+ CD21^low memory B cells in patients with Mixed Cryoglobuliemia
HIV infection	[29]	IgM⁺ CD21^low Tissue-like memory B cells increased in blood of viremic patients
Malaria infection	[86]	IgM⁺ memory B cells detected during infection
CVID	[32, 95]; [30]	IgM⁺ CD21^low B cells with low SHM and poly- and auto-reactivity associated with splenomegaly
SLE	[89]	IgM^low CD21^low B cells a present in the periphery of SLE patients