(A) Mean and standard error of the mean for the total number of cells labeled with RFRP-3-Ir or with Kp-Ir across the 4-day estrous cycle and in female Syrian hamsters either fed ad libitum or food-restricted to 75% of their ad libitum intake for eight days. Tissue was collected from groups representing every day of the four-day estrous cycle. (B) Mean and standard error of the mean for the total number of cells labeled with RFRP-3-Ir in separate groups of female Syrian hamsters that were either fed ad libitum or food restricted to 75% of their ad libitum food intake for eight days. Half of each group was infused intracerebroventricularly with either saline or RFRP-3.