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. Author manuscript; available in PMC: 2019 Apr 1.
Published in final edited form as: Biochim Biophys Acta. 2017 Jun 15;1864(4 Pt B):1245–1253. doi: 10.1016/j.bbadis.2017.06.006

Figure 4. PDGRF signaling pathway.

Figure 4

Quiescent cells express PDGFRα in primary cilia. Its activation induces ERK1/2 phosphorylation by induction of MEK1/2 and activation of AKT through PI3K resulting in cell cycle entry.