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Table 1.

Cytokines and receptors driving cutaneous inflammation

Cytokine Receptor Infection Skin inflammatory phenotype(s)
IL-17A and IL-17F IL-17RA/RC Candida albicans, Staphylococcus aureus Psoriasis, atopic dermatitis, skin cancer
IL-17B IL-17RB/? Undefined Undefined
IL-17C IL-17RA/RE S. aureus Psoriasis
IL-17D Undefined Undefined Undefined
IL-17E (IL-25) IL-17RA/RB Undefined Psoriasis, atopic dermatitis

IL, Interleukin.