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. 2017 Dec 11;8:1741. doi: 10.3389/fimmu.2017.01741

Figure 4.

Figure 4

Figure 4

Stimulatory effect of Plesiomonas shigelloides LA (I-IV) on the productions of the proinflammatory cytokines, TNF-α (A), IL-1β (B), and IL-6 (C), by differentiated human THP-1 macrophages. Statistically significant differences are marked with symbols: p < 0.05 (■/*/▲/●), p < 0.01 (■■/**/▲▲/●●), and p < 0.001 (■■■/***/▲▲▲/●●●), where ■, *, ▲, and ● refer to lipopolysaccharide (LA) I, LA II, LA III, and LA IV, respectively. Escherichia coli O55 LA (LA O55) was used as the positive control. C- Unstimulated cells cultured in the presence of triethalamine (TEA). P values were calculated by ANOVA.