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. 2017 Dec 11;8:665. doi: 10.3389/fneur.2017.00665

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Copyright © 2017 Zwergal, Günther, Brendel, Beck, Lindner, Xiong, Eilles, Unterrainer, Albert, Becker-Bense, Brandt, Ziegler, la Fougère, Dieterich and Bartenstein.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Correlative analysis of SUV [¹⁸F]GE180 uptake in the ipsilesional vestibular nucleus (VN) and behavioral scores. (A) [¹⁸F]GE180 uptake on day 7 post-unilateral labyrinthectomy (UL) correlated negatively with the daily changes in postural asymmetry scores of UL rats (N = 10). (B) The negative correlation between translocator protein (TSPO) activation in the ipsilesional VN and the degree of compensation was still present for [¹⁸F]GE180 uptake on day 15 post-UL (N = 9 rats). (C) Exemplary autoradiography at the level of the VN and facial nucleus (FN) (including anatomical verification by histology) from a rat with very fast vestibular compensation (VC) until death on day 7 (green, upper image, high [¹⁸F]GE180 uptake) and another slice from a rat with very slow VC until death on the same day (red, lower image, low [¹⁸F]GE180 uptake).