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. 2017 Dec 11;8:665. doi: 10.3389/fneur.2017.00665

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Copyright © 2017 Zwergal, Günther, Brendel, Beck, Lindner, Xiong, Eilles, Unterrainer, Albert, Becker-Bense, Brandt, Ziegler, la Fougère, Dieterich and Bartenstein.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Quantitative ROI-based analysis of ex vivo [¹⁸F]GE180 autoradiography after UL and SHAM-UL. Significant increases of [¹⁸F]GE180 uptake were found in the ipsilesional VN on days 7 and 15 after UL, when compared to contralateral, but no significant differences were observed in the VN of SHAM-UL. [¹⁸F]GE180 uptake was consistently elevated in the ipsilateral FN on days 7 and 15 after UL and SHAM-UL, when compared to contralateral (UL/SHAM-UL: N = 4 rats, respectively, per time point). UL, unilateral labyrinthectomy; ips, ipilesional; contr, contralesional; VN, vestibular nucleus; FN, facial nucleus; ROI, region of interest. *p < 0.05 ipsilateral versus contralateral; ^#p < 0.05 UL versus SHAM-UL.