Fig. 7.

Synthesis of precursor (4) for nM5- lipoxygenase inhibitor. a Reaction conditions: To a 20 mmol of benzyl azide (in dichloromethane) was added TfOH (1.1 equiv.) followed by 4-fluorostyrene (2.0 equiv.) at 0 °C and allowed to stir for 1 h. b Reaction conditions: 3 (0.2 mmol), cat. Fe-L₁@EGO-900 (8 mol%), t-BuOK (10 mol%), and mesitylene (2 mL) heated at 145 °C for 24 h