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. 2017 Dec 15;7:17651. doi: 10.1038/s41598-017-17744-w

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Dipyridamole abolishes the inhibitory effects of AICAR on TNF-α-induced CFB expression. (A) RPE cells were preincubated with 8 μM DPY for 1 hour and then treated with 2 mM AICAR for 1 hour followed by 10 ng/mL TNF-α for 24 hours. Western blot demonstrating the expression level of CFB in supernatants and cell lysates. (B) Densitometry of CFB in RPE cell lysate in A is shown. Representative blots are shown. *p < 0.05.