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. 2017 Dec 16;17:861. doi: 10.1186/s12885-017-3884-2

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Gene expression microarray analyses of the target genes of PLK1 target genes in bladder cancer cells. The A heatmap (a) and volcano map (b) showed showing the differentially expression expressed genes analyzed by the Affymetrix HTA 2.0 Array in control siRNA group and PLK1 siRNA groups. C: control siRNA, P: PLK1 siRNA. The A summary of the top 20 changaltered biological processes or pathways after knockdown of PLK1 knockdown in T24 cells by using GO biological process analysis (c) and KEGG pathway analysis (d). Network analysis of the pathways after knockdown of PLK1 knockdown in T24 cells (e)