Table 3.
Univariable and multivariable analysis of possible predictors of the biological behavior of solitary fibrous tumors of the pleura
| Variable | Univariable analysis | Multivariable analysis | ||
|---|---|---|---|---|
| HR (95% CI) | p-value | HR (95% CI) | p-value | |
| Tumor size ≥10 cm | 8.8 (1.8–43.5) | 0.008 | 81.8 (1.7–4016.8) | 0.027 |
| Necrosis | 3.4 (0.8–14.6) | 0.089 | 1.7 (0.1–18.4) | 0.7 |
| MIB-1 ≥ 10% | 13.3 (3.6–50.7) | < 0.001 | 12.3 (1.1–139.5) | 0.043 |
| Mitoses ≥4/10 HPF | 13.1 (1.6–112.0) | 0.019 | 36.6 (1.2–1103.7) | 0.039 |
| Atypical location | 1.6 (0.2–13.4) | 0.641 | ||
| Non-pedunculated | 196.6 (0.0–126,601,532.0) | 0.439 | ||
| Pleomorphism | 9.8 (2.2–44.5) | 0.003 | 11.2 (0.6–22.3) | 0.1 |