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. 2017 Dec 16;7:71. doi: 10.1186/s13578-017-0197-8

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Heterogenous aggregate formation in suspension culture of HKCSCs before protein isolation for mass spectrometry and Western blotting at day 6 of the culture prove resistance of HKCSCs to sorafenib in hypoxia and axitinib in normoxia. Reduced proliferation rates in lower oxygen tension is shown. Resistant HKCSCs are marked with a black square. Magnification: 4×, scale bar = 200 µm