Table 1. Physiological characteristics of rats in all the study groups.
| Non-cachexia controls | Non-cachexia control-formoterol | Cancer- cachexia | Cancer-cachexia- formoterol | |
|---|---|---|---|---|
| N = 9 | N = 9 | N = 10 | N = 10 | |
| Initial body weight (g) | 129.2 ± 6.4 | 122.31 ± 9.3 | 125.1 ± 11.4 | 124.5 ± 6.6 |
| Tumor weight (g) | NA | NA | 42.1 ± 8.8 | 38.8 ± 8.9 |
| Final body weight (g) | 166.6 ± 9.7 | 159.5 ± 9.3 | 116.7 ± 11.3*** | 127.2 ± 8.3 |
| Body weight gain (%) | +29.0 ± 2.5 | +30.6 ± 3.3 | −6.6 ± 5.0*** | +2.2 ± 5.5§§§ |
| Diaphragm weight (mg/100 g IBW) | 285.8 ± 33.9 | 325.6 ± 51.3 | 113.5 ± 24.2*** | 181.7 ± 106.3 |
| Gastrocnemius weight (mg/100 g IBW) | 663.3 ± 40.3 | 709.9 ± 60.3 | 544.6 ± 20.7*** | 632.4 ± 22.9§§§ |
Notes.
Variables are presented as mean ± standard deviation.
Abbreviations
- NA
- not applicable
- g
- gram
- mg
- milligram
- IBW
- initial body weight
Statistical significance:
***
p ≤ 0.001 between non-cachexia controls and cancer-cachexia rats.
§§§
p ≤ 0.001 between cancer-cachexia rats and cancer-cachexia rats treated with formoterol.