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. 2017 Dec 13;12:8779–8799. doi: 10.2147/IJN.S150196

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© 2017 Zhang et al. This work is published and licensed by Dove Medical Press Limited

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Antitumor activity of PTX-CMs in BEL7402 xenograft mice.

Notes: Tumor-growth curves of early-stage (A) and late-stage (C) tumor model. Body weight changes in early-stage (B) and late-stage (D) tumor model. Data are presented as mean ± SD (n=8). (E) Survival rates of mice in different treatment groups within 28 days. Data are presented as mean ± SD (n=8). (F) Representative images of mice treated with PTX-CMs at PTX dose of 30 mg/kg in late-stage tumor model at 0, 4, 8, 18, 25, and 32 days. Arrows indicate time when mice received intravenous injections.

Abbreviations: PTX-Ms, paclitaxel-loaded monomethoxy(polyethylene glycol)-block-poly(d,l-lactide) micelles; CMs, sodium cholate and monomethoxy(polyethylene glycol)-block-poly(d,l-lactide) micelles.