Table 1.
Baseline characteristics of patients according to their medical equipment
| Characteristics | Total patients | LTOT | NIV | CPAP | NE |
|---|---|---|---|---|---|
| Sample size (n) | 298 | 109 | 84 | 25 | 80 |
| Men to women ratio (n) | 199/99 | 73/36 | 56/28 | 20/5 | 50/30 |
| Age (years) | 63.8±11.0 | 64.8±11.8 | 64.9±8.8 | 64.9±11.9 | 60.7±11.2 |
| BMI (kg/m2) | 27.0±7.6 | 24.9±6.5b | 29.4±9.0c | 33.6±5.5c | 25.6±6.3b |
| FEV1 (L) | 1.117±0.536 | 0.930±0.423d | 0.962±0.464d | 1.409±0.575 | 1.380±0.563 |
| FEV1 (% theoretical value) | 40.9±17.1 | 35.0±14.9d | 34.3±14.5d | 53.0±16.1 | 49.9±16.1 |
| FVC (% theoretical value) | 66.2±20.1 | 59.9±19.8d | 60.6±18.4a | 74.7±16.6 | 75.8±18.5 |
| FEV1/FVC | 50.6±12.8 | 46.2±11.7d | 48.6±12.4e | 58.3±9.1 | 54.9±12.9 |
| Moderate airflow limitation (50%≤FEV1<80%), n (%) | 71 (23.8) | 15 (13.8)d | 10 (11.9)d | 12 (48.0) | 34 (42.5) |
| Severe airflow limitation (30%≤FEV1<50%), n (%) | 132 (44.3) | 48 (44.0) | 35 (41.7) | 11 (44.0) | 38 (47.5) |
| Very severe airflow limitation (FEV1<30%), n (%) | 95 (31.9) | 46 (42.2)d | 39 (46.4)d | 2 (8.0) | 8 (10.0) |
| TLC (% theoretical value) | 108.9±26.3 | 106.8±31.5 | 112.8±25.1 | 102.3±17.0 | 109.1±24.4 |
| Short-acting β2-agonists, n | 160 | 69 | 47 | 7 | 37 |
| Long-acting β2-agonists, n | 120 | 50 | 30 | 5 | 35 |
| Long-acting anticholinergic, n | 193 | 80 | 65 | 9 | 39 |
| Bronchodilator associated with corticosteroids, n | 145 | 58 | 40 | 11 | 36 |
| Inhaled corticosteroids, n | 46 | 21 | 17 | 3 | 5 |
| Oral corticosteroids, n | 61 | 38 | 12 | 2 | 9 |
Notes: Data shown as n, mean ± standard deviation, or n (%).
a
Significantly different from NE (p<0.05).
b
Significantly different from CPAP and NIV (p<0.05).
c
Significantly different from all others groups (p<0.05).
d
Significantly different from CPAP and NE (p<0.05).
e
Significantly different from CPAP (p<0.05).
Abbreviations: BMI, body mass index; CPAP, continuous positive airway pressure; FEV1, forced expiratory volume in 1 second; FVC, forced vital capacity; LTOT, long-term oxygen therapy; n, sample size; NE, no equipment; NIV, noninvasive ventilation; TLC, total lung capacity.