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. 2016 Jun 7;8(61):102852–102867. doi: 10.18632/oncotarget.9913

Figure 7. Parkin overexpression ameliorates the clearance of damaged mitochondria in CS-A cells.

Figure 7

(A, B) Top: mitochondrial DRP1 quantification (DRP1/HSP60 positive cells) in A. CS3BE and CS3BE-wtCSA cells (**p < 0.01, ***p < 0.001) and B. normal (N2RO) and CS-A (CS24PV) in primary fibroblasts (*p < 0.05, **p < 0.01, ***p < 0.001) before and after Parkin overexpression in basal conditions and after 20 µM CCCP treatment for 16h. Bottom: immunofluorescence analysis of DRP1 and LC3 A. and DRP1 and HSP60 B. localization before and after Parkin overexpression, in basal conditions and after 20 µM CCCP treatment for 16h.