Table 2. Immunohistochemical results and cell of origin (COO) determined according to Hans’s algorithm in PB-DLBCL.
SAMPLE | CD10 | CD20 | BCL6 | BCL2 | MUM1 | Ki67 | COO |
---|---|---|---|---|---|---|---|
01 | + | + | + | + | ND | 96% | GCB |
03 | – | + | + | + | – | 70% | GCB |
04 | + | + | + | – | – | 80% | GCB |
05 | + | + | + | + | ND | 80% | GCB |
06 | ND | + | + | + | – | 80% | GCB |
07 | ND | + | + | + | – | 90% | GCB |
08 | – | + | + | + | – | 80% | GCB |
09 | – | + | + | + | – | 85% | GCB |
02 | – | + | – | + | ND | 59% | Non-GCB |
10 | – | + | + | + | + | 80% | Non-GCB |
11 | – | + | – | – | + | 100% | Non-GCB |
12a | ND | + | ND | ND | ND | 98% | ND |
12b | – | + | + | + | + | 98% | Non-GCB |
15 | ND | + | + | + | + | 80% | Non-GCB |
16 | – | + | + | + | + | 80% | Non-GCB |
17 | – | + | + | + | + | 80% | Non-GCB |
13 | ND | + | ND | ND | ND | 90% | ND |
14 | – | + | + | + | ND | 100% | ND |
GCB: germinal center B-cell; non-GCB: non-germinal center B-cell, ND: No data.