Table 2. Results for lipid metabolism genes that showed significant association with survival both in the TCGA and KMplot.com data sets.
| Gene | TCGA p-value |
KMplot.com p-value |
Expression poor survival | CNA p-value |
Enzyme | KEGG pathway |
|---|---|---|---|---|---|---|
| ABCD1 | 0.043 | 0.010 | low | NA | ATP-Binding Cassette, Sub-Family D (ALD), Member 1 | hsa04146: peroxisome |
| ADH1B | 0.027 | <0.001 | high | 0.368 | Alcohol Dehydrogenase 1B (Class I), Beta Polypeptide | hsa00071: fatty acid degradation |
| ASAH1 | 0.003 | 0.007 | high | 0.067 | N-Acylsphingosine Amidohydrolase (Acid Ceramidase) 1 | hsa00600: sphingolipid metabolism |
| CEL | 0.013 | 0.022 | low | 0.397 | Carboxyl ester lipase | hsa00561: glycerolipid metabolism |
| LPIN2 | 0.002 | 0.042 | low | 0.326 | Lipin 2 | hsa00561: glycerolipid metabolism; hsa00564: glycerophospholipid metabolism |
| PLA2G2D | 0.002 | 0.003 | low | 0.304 | Phospholipase A2, Group IID | hsa00564: glycerophospholipid metabolism |
Also the p-values from the copy number analyses (CNA) are shown.