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. 2017 Aug 3;8(61):102989–103003. doi: 10.18632/oncotarget.19900

Figure 6. Immunohistochemical analysis of HIF-1α in rat renal tissues.

Figure 6

(A) Representative images (400×) of immunohistochemically stained renal tissue sections from control, cisplatin, cisplatin + PNS, 2ME2 + cisplatin and 2ME2 + cisplatin + PNS groups of rats. (B) The expression of HIF-1α protein and (C) nuclear localization of HIF-1α in renal tissues from control, cisplatin, cisplatin + PNS, 2ME2 + cisplatin and 2ME2 + cisplatin + PNS groups of rats are shown. Note: Black arrows denote nuclear HIF-1α staining. Data are represented as mean ± SD (n = 6). * denotes P < 0.05 compared with the cisplatin group; # denotes P < 0.05 when compared with the 2ME2 + cisplatin group.