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. 2017 Oct 3;8(61):103032–103046. doi: 10.18632/oncotarget.21460

Figure 4. The alterations in TCA metabolic pathway in SPOP-mutated cohort.

Figure 4

(A–B) The normalized peak intensity values of fumarate (A) and malate (B). (CD) The expression of FH (C) and MDH2 (D) transcripts. (E) A correlation network was constructed based on PCC between transcripts and metabolites in TCA cycle, with the absolute value of correlation coefficient more than 0.6. *p < 0.05 compared with the ANT tissues. S-PCT, SPOP-mutated PCT tissues; S-ANT, SPOP-mutated ANT tissues.