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. 2017 Oct 13;8(61):103393–103409. doi: 10.18632/oncotarget.21900

Figure 2. DH attenuates ET-1 induced cell area enlargement and elevation of ACTN2 and TNNT2 contents on hypertrophic hiPS-CMs.

Figure 2

(A) Representative images of the HCA analysis of hypertrophic hiPS-CMs treated by a various dose of DH for the evaluation of cell area, ACTN2 and TNNT2 contents. (B) Cell area of hypertrophic hiPS-CMs were alleviated by DH treatment at 1.25, 2.5 and 5.0 μL/mL. (C) ACTN2 content of hypertrophic hiPS-CMs were suppressed by DH treatment at 1.25, 2.5 and 5.0 μL/mL. (D) TNNT2 content of hypertrophic hiPS-CMs were suppressed by DH treatment at 0.63, 1.25, 2.5 and 5.0 μL/mL. **P < 0.05: versus ET-1 group; ##P < 0.05: versus vehicle group.