Table 3. Genotype distributions of the IL-17A polymorphisms between the IS patients and the control group.
| Polymorphisms | Controls | Cases | Logistic regression | |
|---|---|---|---|---|
| n=443 (%) | n=392 (%) | OR (95% CI)† | P value† | |
| rs1974226 | ||||
| CC | 394 (88.9) | 359 (91.6) | 1.00 (Ref) | |
| CT | 48 (10.9) | 31 (7.9) | 0.84 (0.40∼1.76) | 0.643 |
| TT | 1 (0.2) | 2 (0.5) | 2.11 (0.14∼32.99) | 0.595 |
| CT/TT vs. CC | 0.89 (0.43∼1.82) | 0.744 | ||
| CC/CT vs. TT | 2.27 (0.21∼25.09) | 0.505 | ||
| rs3748067 | ||||
| CC | 364 (82.2) | 323 (82.4) | 1.00 (Ref) | |
| CT | 77 (17.4) | 65 (16.6) | 1.02 (0.59∼1.77) | 0.951 |
| TT | 2 (0.4) | 4 (1.0) | 1.49 (0.15∼14.81) | 0.735 |
| CT/TT vs. CC | 1.04 (0.60∼1.78) | 0.898 | ||
| CC/CT vs. TT | 1.48 (0.15∼14.74) | 0.736 | ||
| rs2275913 | ||||
| AA | 121 (27.3) | 72 (18.4) | 1.00 (Ref) | |
| GA | 235 (53.1) | 231 (58.9) | 1.72 (1.05∼2.81) | 0.032 |
| GG | 87 (19.6) | 89 (22.7) | 1.99 (1.08∼3.67) | 0.028 |
| GA/GG vs. AA | 1.78 (1.11∼2.86) | 0.017 | ||
| AA/GA vs. GG | 1.36 (0.82∼2.25) | 0.229 | ||
OR, odds ratio; CI, confidence interval; Ref, reference category; †, Adjusted by age, gender, hypertension, diabetes mellitus, TG, LDL-C, HDL-C, and TCH.