Table 4. Genotype distributions of the IL-17A rs2275913 polymorphism in different populations.
| Population | n | Genotypes (%) | MAF (%) | Ethnic | |||
|---|---|---|---|---|---|---|---|
| AA | GA | GG | G | A | |||
| Present data | 443 | 121 (27.3) | 235 (53.1) | 87 (19.6) | 409 (46.2) | - | Guangxi |
| HM-HCB | 86 | 14 (16.3) | 52 (60.5) | 20 (23.2) | - | 80 (46.5) | Asian |
| HM-CHB | 82 | 26 (31.7) | 38 (46.3) | 18 (22.0) | 74 (45.1) | - | Asian |
| HM-CHD | 170 | 54 (31.8) | 78 (45.9) | 38 (22.3) | 154 (45.3) | - | Asian |
| HM -JPTΔ | 172 | 36 (20.9) | 84 (48.9) | 52 (30.2) | - | 156 (45.3) | Asian |
| HM-LWKΔ | 180 | - | 22 (12.2) | 158 (87.8) | - | 22 (6.1) | Asian |
| HM-MEXΔ | 100 | 2 (2.0) | 52 (52.0) | 46 (46.0) | - | 56 (28.0) | Asian |
| HM-GIHΔ | 176 | 36 (20.4) | 70 (39.8) | 70 (39.8) | - | 142 (40.3) | Asian |
| HM-YRIΔ | 226 | - | 30 (13.3) | 196 (86.7) | - | 30 (6.6) | African |
| HM-ASWΔ | 98 | - | 18 (18.4) | 80 (81.6) | - | 18 (9.2) | African |
| HM-MKKΔ | 286 | 2 (0.7) | 28 (9.8) | 256 (89.5) | - | 32 (5.6) | African |
| HM-CEUΔ | 226 | 28 (12.4) | 104 (46.0) | 94 (41.6) | - | 160 (35.4) | European |
| HM-TSIΔ | 176 | 28 (15.9) | 78 (44.3) | 70 (39.8) | - | 134 (38.1) | European |
Δ, Comparing with our present data, P < 0.05; MAF, minor allele; HM, HapMap; CEU, Utah residents with northern and western European ancestry; HCB, Han Chinese in Beijing, China; CHB, Han Chinese in Beijing, China; CHD, Chinese in Metropolitan Denver, Colorado; JPT, Japanese in Tokyo, Japan; LWK, Luhya in Webuye, Kenya; MEX, Mexican ancestry in Los Angeles, California; GIH, Gujarati Indians in Houston, Texas; YRI, Yoruba in Ibadan, Nigeria. ASW, African ancestry in Southwest USA; MKK, Maasai in Kinyawa, Kenya; TSI, Toscans in Italy.