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. 2017 Oct 6;8(61):103518–103534. doi: 10.18632/oncotarget.21568

Table 2. Univariate and multivariate analyses of overall survival (OS).

Characteristics Median OS(month) Univariate analysis Multivariate analysis
Log-rank P HR(95%CI) P
Marital status 544.62 <.0001
 Married 14 Ref.
 Divorced/separated 11 1.15(1.12, 1.18) <.0001
 Widowed 10 1.16(1.14, 1.19) <.0001
 Never married 11 1.15(1.12, 1.18) <.0001
Gender 530.73 <.0001
 Male 11 Ref.
 Female 14 0.81(0.80, 0.83) <.0001
Age 1486.10 <.0001
 <60 14 Ref.
 60-69 14 1.13(1.11, 1.16) <.0001
 70-79 12 1.34(1.30, 1.37) <.0001
 ≥80 8 1.65(1.61, 1.70) <.0001
Race 131.47 <.0001
 White 12 Ref.
 Black 10 1.01(0.98, 1.03) 0.5546
 Others 14 0.87(0.84, 0.89) <.0001
Diagnosis year 53.38 <.0001
 2004-2008 12 Ref.
 2009-2012 13 0.93(0.91, 0.95) <.0001
Median household income 116.53 <.0001
 Quartile 4 13 Ref.
 Quartile 3 13 0.99(0.97, 1.02) 0.6257
 Quartile 2 12 1.05(1.03, 1.08) <.0001
 Quartile 1 11 1.05(1.02, 1.07) 0.0003
Grade 8018.64 <.0001
 I 64 Ref.
 II 32 1.35(1.28, 1.42) <.0001
 III 13 1.55(1.47, 1.63) <.0001
 IV 10 1.66(1.54, 1.79) <.0001
 Unknown 8 1.49(1.42, 1.57) <.0001
TNM stage 21640.45 <.0001
 I 63 Ref.
 II 30 1.60(1.53, 1.67) <.0001
 III 13 1.85(1.79, 1.90) <.0001
 IV 6 3.23(3.13, 3.33) <.0001
Histology 2490.73 <.0001
 adenocarcinoma 16 Ref.
 squamous carcinoma 13 1.14(1.11, 1.16) <.0001
 Others 8 1.15(1.13, 1.18) <.0001
Surgery 19418.35 <.0001
 Yes 71 Ref.
 No 8 2.67(2.59, 2.76) <.0001
Radiotherapy 1563.04 <.0001
 Yes 10 Ref.
 No 15 1.14(1.12, 1.16) <.0001