Table 7. Subgroup analyses stratified by TNM stage for NSCLC patients without surgery (CSS).
| Characteristics | Stage I | Stage II | Stage III | Stage IV |
|---|---|---|---|---|
| Marital status | ||||
| Married | Ref. | Ref. | Ref. | Ref. |
| Divorced/separated | 1.21(1.07, 1.37)a | 1.11(0.91, 1.35) | 1.13(1.07, 1.20)a | 1.13(1.09, 1.17)a |
| Widowed | 1.14(1.03, 1.27)b | 1.09(0.91, 1.31) | 1.17(1.11, 1.23)a | 1.12(1.08, 1.17)a |
| Never married | 1.03(0.89, 1.18) | 1.09(0.89, 1.35) | 1.11(1.04, 1.18)a | 1.13(1.09, 1.17)a |
| Gender | ||||
| Male | Ref. | Ref. | Ref. | Ref. |
| Female | 0.81(0.75, 0.89)a | 0.89(0.77, 1.03) | 0.83(0.80, 0.87)a | 0.85(0.83, 0.87)a |
| Age | ||||
| <60 | Ref. | Ref. | Ref. | Ref. |
| 60-69 | 1.20(1.00, 1.44) | 1.31(1.03, 1.66)b | 1.08(1.02, 1.14)a | 1.11(1.07, 1.14)a |
| 70-79 | 1.37(1.15, 1.63)a | 1.36(1.09, 1.71)a | 1.22(1.15, 1.29)a | 1.22(1.18, 1.26)a |
| ≥80 | 1.50(1.26, 1.79)a | 1.80(1.42, 2.30)a | 1.51(1.41, 1.60)a | 1.41(1.35, 1.47)a |
| Race | ||||
| White | Ref. | Ref. | Ref. | Ref. |
| Black | 0.96(0.85, 1.09) | 1.03(0.83, 1.27) | 1.00(0.94, 1.05) | 0.98(0.95, 1.02) |
| Others | 0.93(0.79, 1.09) | 1.10(0.84, 1.44) | 0.88(0.82, 0.94)a | 0.82(0.79, 0.86)a |
| Diagnosis year | ||||
| 2004-2008 | Ref. | Ref. | Ref. | Ref. |
| 2009-2012 | 0.81(0.74, 0.88)a | 0.90(0.78, 1.03) | 0.93(0.90, 0.97)a | 0.95(0.92, 0.97)a |
| Median household income | ||||
| Quartile 4 | Ref. | Ref. | Ref. | Ref. |
| Quartile 3 | 1.00(0.89, 1.13) | 1.32(1.07, 1.61)a | 1.04(0.98, 1.10) | 1.02(0.98, 1.06) |
| Quartile 2 | 0.91(0.81, 1.03) | 1.13(0.91, 1.40) | 1.08(1.02, 1.14)a | 1.04(1.01, 1.08)b |
| Quartile 1 | 0.93(0.82, 1.05) | 1.21(0.98, 1.50) | 1.04(0.99, 1.10) | 0.99(0.95, 1.02) |
| Grade | ||||
| I | Ref. | Ref. | Ref. | Ref. |
| II | 1.51(1.23, 1.85)a | 1.42(0.91, 2.22) | 1.23(1.07, 1.41)a | 1.29(1.17, 1.41)a |
| III | 1.51(1.24, 1.85)a | 1.50(0.97, 2.32) | 1.30(1.14, 1.49)a | 1.54(1.41, 1.69)a |
| IV | 1.36(0.90, 2.06) | 1.54(0.84, 2.83) | 1.45(1.20, 1.74)a | 1.65(1.46, 1.87)a |
| Unknown | 1.24(1.02, 1.50)b | 1.41(0.92, 2.16) | 1.24(1.09, 1.41)a | 1.48(1.35, 1.61)a |
| Histology | ||||
| adenocarcinoma | Ref. | Ref. | Ref. | Ref. |
| squamous carcinoma | 1.49(1.34, 1.66)a | 1.33(1.11, 1.58)a | 1.18(1.12, 1.23)a | 1.09(1.05, 1.13)a |
| Others | 1.22(1.10, 1.36)a | 1.23(1.02, 1.48)b | 1.09(1.04, 1.14)a | 1.15(1.12, 1.18)a |
| Radiotherapy | ||||
| Yes | Ref. | Ref. | Ref. | Ref. |
| No | 2.01(1.85, 2.18)a | 1.63(1.41, 1.88)a | 1.67(1.60, 1.74)a | 0.97(0.95, 0.99)b |
a: P<0.01; b: P<0.05.