Table 2. ZB716 metabolites detected in rat plasma, urine, and feces samples.
Plasma | Feces | Urine | |
---|---|---|---|
ZB716 | + | + | + |
FU | + | + | + |
FU-17-ketone | + | + | + |
ZB716-17-ketone | + | + | + |
FU-MO1 | - | + | - |
FU-MO2 | - | + | - |
FU-MO3 | - | - | - |
FU-sulfone | + | + | + |
ZB716-sulfone | + | + | - |
ZB716-17-sulfate | - | + | - |
FU-3-sulfate | - | + | - |
FU-17-sulfate (from ZB716-17-sulfate) | - | + | - |
ZB716-17-glucuronide | - | - | + |
FU-17-glucuronide (from ZB716-17-glucuronide) | - | + | + |
FU-3-glucuronide conjugate | - | - | + |