Figure 3. Diexf heterozygous animals are not sensitive to sub-lethal ionizing radiation.
(A) Western blot showing Diexf expression in different mouse tissues. Vinculin was used to evaluate protein loading. SI, Small intestine; LI, Large Intestine; St, Stomach; Li, Liver; Br, Brain; Sp, Spleen; Th, Thymus; He, Heart; Lu, Lung; Ki, Kidney; Te, Testes. (B) Survival curve of Diexf+/∆26 animals after 6 Gy radiation. Wild type and Mdm2P2/P2 animals were used as negative and positive controls respectively.