Table 2. Homozygous deletion of Diexf is embryonic lethal at peri-implantation stage (E4.5-E5.5) in mice.
Diexf+/− X Diexf+/− : Observed (Expected) | |||||
---|---|---|---|---|---|
Allele | Age | Diexf+/+ | Diexf+/− | Diexf−/− | Empty Decidua |
Diexf13ins | P21 | 7 (6) | 15 (11) | 0 (6) | - |
Diexf∆26 | P21 | 19 (12) | 29 (24) | 0 (12) | - |
Diexf∆26 | E14.5 | 4 (3) | 9 (7) | 0 (3) | 0 |
Diexf∆26 | E9.5 | 4 (4) | 10 (7) | 0 (4) | 4 |
Diexf∆26 | E7.5 | 9 (6) | 15 (12) | 0 (6) | 6 |
Heterozygous crosses between Diexf+/− mice (two lines) and observed vs expected numbers for all genotype at various stages. P21 = 21 days after birth. E = embryonic day. All expected numbers are rounded to the nearest integer.