Table 3. Conventional chemotherapy in patients with T-PLL.
N | ORR (%) | CR (%) | Median OS (months) | |
---|---|---|---|---|
alkylating agents (1) | 32 | 31 | 3 | 7.5a |
Pentostatin (90)b | 55 | 45 | 9 | 17.5/9c |
Pentostatin (91)d | 25 | 8 | 0 | 4 |
Bendamustine (102)b | 15 | 53.3 | 20 | 8.7 |
a median OS of the entire group of 78 patients treated by various therapies, b relapsed/refractory and treatment-naïve patients, c median OS: 17.5 months for responders and 9 months for non-responders, d relapsed/refractory patients.