Table 1.
Signaling governing nervous system transition zones
| MUTANT/KNOCK-DOWN | EXPRESSION | PHENOTYPE | ORGANISM | REFERENCES |
|---|---|---|---|---|
| Ntn1/Dcc | Dorsolateral spinal cord | Interneuron exit the DREZ ectopically | Mouse | 28 |
| Ntn5/Dcc | BC cells | Ectopic motor neurons | Mouse | 29 |
| Krox20 | BC cells, SCs | Ectopic motor neurons and CNS glia in the motor nerve root | 11 | |
| Nkx2.2 | Perineurial glia | Ectopic motor neurons in the motor nerve root | Zebrafish/Mouse | 9, 12 |
| Npn1 | Motor neurons | Ectopic motor neurons in the motor nerve root | Zebrafish | 33 |
| Npn2 | Motor neurons | Ectopic motor neurons in the motor nerve root | Chick/Mouse | 8, 27 |
| Sema6a | BC cells | Ectopic motor neurons in the motor nerve root | Mouse | 27 |
| Sema3ab | Posterior half of the somite | Mispositioned motor neurons | Zebrafish | 33 |
| PlexinA3 (sidetracked) | Motor neurons | Mispositioned MEP | Zebrafish | 30–32 |
| Erbb3 | PNS glia | Ectopic oligodendrocytes along motor nerves | Zebrafish | 41 |