Table 1.

Patient characteristics^a

	Thiamine n = 34	No Thiamine n = 19	P-value
Demographics
Age (years)	57 (49, 64)	62 (44, 68)	0.74
Gender (female)	11 (32)	8 (42)	0.56
Race (white)	23 (68)	10 (53)	0.47
Body mass index (kg/m2)	28 (22, 33)	25 (24, 26)	0.19
Alcohol use disordersb
Alcohol dependence syndrome	26 (76)	13 (68)	0.53
Alcoholic liver disease	22 (65)	11 (58)	0.77
Alcohol-induced mental disorders	5 (15)	0 (0)	0.15
Alcoholic cardiomyopathy	0 (0)	1 (5)	0.36
Co-morbidities
Heart failure	5 (15)	2 (11)	1.00
Hypertension	18 (53)	8 (42)	0.57
Diabetes	8 (24)	5 (26)	1.00
Renal disease	3 (9)	3 (16)	0.65
Liver disease	23 (68)	11 (58)	0.56
COPD	7 (21)	2 (11)	0.46
Laboratory values
Hemoglobin (g/dL)	11.0 (10.2, 13.5)	10.7 (8.1, 13.8)	0.83
White blood cells (103)	10.8 (5.2, 14.0)	11.7 (9.0, 17.0)	0.17
Bicarbonate (mEq/L)	15 (11, 19)	16 (12, 21)	0.43
Lactate (mmol/L)	7.1 (5.2, 10.2)	7.9 (5.5, 10.5)	0.67
Platelets (103)	92 (53, 159)	178 (80, 280)	0.04
Creatinine (mg/dL)	2.0 (1.1, 3.1)	1.6 (1.3, 3.5)	0.60
Glucose (mg/dL)	119 (83, 170)	133 (103, 202)	0.37
Potassium (mEq/L)	4.2 (3.7, 4.7)	4.4 (3.8, 4.9)	0.56
AST (IU/L)	153 (34, 611)	131 (39, 206)	0.84
ALT (IU/L)	49 (20, 174)	64 (34, 91)	0.59
Bilirubin (mg/dL)	4.2 (1.0, 8.7)	1.9 (0.7, 5.4)	0.50
Interventions/Vital signs
Intubated	27 (79)	18 (95)	0.23
SOFA score	11 (8, 16)	12 (10, 13)	0.54

^aCategorical variables are presented as count (frequency) and continuous variables as median (quartiles). Abbreviations: COPD, chronic obstructive pulmonary disease; AST, aspartate transaminase; ALT, alanine transaminase; SOFA, sepsis-related organ failure assessment.

^bPatients may have more than one diagnosis of alcohol use disorder (see Table S1 in the Supplement).