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Funnel plot with trim and fill method for the association between APOE gene polymorphism and the risk of coronary artery diseases in type 2 diabetes patients under the genetic model of ε3/ε4 vs. ε3/ε3 (A), ε4/ε4+ε3/ε4 vs. ε3/ε3 (B), and ε4 allele vs. ε3 allele (C). Circle represents the included studies; Square represents the possibly missing studies.
