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. 2017 Dec 12;9:408. doi: 10.3389/fnagi.2017.00408

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Copyright © 2017 Carter, France, Crean and Singhrao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Venn diagram shows the number of susceptibility genes (GWASdb) and their percentage occurrence within the P. gingivalis/host interactome that are common or specific to various combinations of atherosclerosis (Athero), type 2 diabetes (Diab), hypertension (hyper) and Alzheimer's (Alz), The Venn diagram is for data from GWASdb. The genes in boxes refer to GWAS genes from the more stringent NCBI-EBI data that are also part of the P. gingivalis/host interactome. The percentages are those of the sum of the interactome/susceptibility gene overlaps for all diseases represented in the figure (atherosclerosis+ type 2 diabetes + hypertension+ Alzheimer's gene/interactome overlaps).