Table 1.
List of antimicrobials recommended by the European Centre for Disease Prevention and Control (ECDC) and the United States Centers for Disease Prevention and Control (CDC) for standard definitions of multidrug resistance, extensive drug resistance and pandrug resistance for Acinetobacter spp. (Magiorakos et al., 2012) along with the antimicrobial agents with available breakpoints as given by the Clinical and Laboratories Standard Institute (CLSI) in its 2017 edition (CLSI, 2017).
| Antimicrobial agent | Inclusion in ECDC-CDC |
|---|---|
| with CLSI breakpoints | recommendation |
| Penicillins | |
| Piperacillin | No |
| β-lactam/β-lactamase inhibitor | |
| Ampicillin/Sulbactam | Yes |
| Piperacillin/Tazobactam | Yes |
| Ticarcillin/Clavulanante | Yes |
| Cephams | |
| Ceftazidime | Yes |
| Cefepime | Yes |
| Cefotaxime | Yes |
| Ceftriaxone | Yes |
| Carbapenems | |
| Doripenem | Yes |
| Imipenem | Yes |
| Meropenem | Yes |
| Lipopeptides | |
| Colistin | Yes |
| Polymyxin B | Yes |
| Aminoglycosides | |
| Gentamicin | Yes |
| Tobramyxin | Yes |
| Amikacin | Yes |
| Netilmycin | Yes |
| Tetracycline | |
| Doxycycline | Yes |
| Minocycline | Yes |
| Tetracycline | Yes |
| Fluoroquinolones | |
| Ciprofloxacin | Yes |
| Levofloxacin | Yes |
| Gatifloxacin | No |
| Folate pathway inhibitors | |
| Trimethoprim-sulfamethoxazole | Yes |
Antimicrobial groups are given in bold.