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. 2017 Dec 12;7:513. doi: 10.3389/fcimb.2017.00513

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Copyright © 2017 Gao, Li, Lin, Lin, Xia, Wang, Bi, Zhu, Hassan, Wang and Feng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Roles of V. cholerae FadR and the new ligand-binding site 2 in bacterial virulence. Effects exerted by V. cholerae FadR on colonization in the infant mouse model. ΔfadR mutants containing vector control, VcfadR and VcfadR (Δ42) were co-inoculated into infant mice with wild-type at 1:1 ratio. After 18-h colonization, the colonized bacteria were enumerated on selective agar plates. Competitive index is calculated as output ratio of mutant to wild-type normalized against input ratio of mutant to wild-type. Horizontal line: mean of CI. ^**Student t-test p < 0.01; ns, no significance.