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(A) Superimposed binding modes of compounds 1 (purple), 2 (pink), 3 (light yellow), 4 (blue) and Ceftriaxone (red) in the active site of PBP 2A from S. aureus (PDB ID 1VQQ); (B) 2D interaction plot of ceftriaxone generated by Discovery Studio Visualizers showing interaction of with key amino acid residues. Conventional hydrogen bonding is shown by green color dotted lines.
