Table 2.
Included trials, participants, interventions, and outcomes.
| Total (n) | Anaesthetic type | Intervention groups (n) | Outcomes | |
|---|---|---|---|---|
| Elgebaly et al., 2011, Egypt | 90 | Spinal | (i) IV magnesium sulphate bolus and 24 hr infusion (30) | (i) Total 24 hr analgesia use (paracetamol) |
| (i) Bupivacaine 0.5% (2 mL) | (ii) 25 µg in 1 mL intrathecal fentanyl plus + NS IV (30) | (ii) Time to first analgesia | ||
| (iii) Normal saline control (30) | (iii) Pain (VAS) score | |||
|
| ||||
| Helmy et al., 2015, Egypt | 60 | General | (i) IV magnesium sulphate bolus (20) | (i) Intraop analgesia requirement (fentanyl) |
| (i) Thiopental 5 mg/kg | (ii) Ketamine 0.3 mg/kg (20) | (ii) Time to first analgesia | ||
| (ii) Fentanyl 100 μg at delivery | (iii) 20 mL normal saline control (20) | (iii) Pain (VAS) score | ||
|
| ||||
| Elrahman and Youssry, 2017, Egypt | 90 | General | (i) IV magnesium sulphate bolus (30) | (i) Total 24 hr analgesia use (morphine) |
| (i) IV propofol 2 mg/kg | (ii) Normal saline control (30) | (ii) Time to first analgesia | ||
| (ii) IV midazolam 1 mg and fentanyl 1 μg/kg at delivery | (iii) Pain (VAS) score | |||
| (iv) Time to ambulation | ||||
|
| ||||
| Maulik et al., 2015, India | 80 | Spinal | (i) IV magnesium sulphate bolus and 24 hr infusion (40) | (i) Rescue analgesia consumption (diclofenac) |
| (i) Bupivacaine 0.5% | (ii) Normal saline control (40) | (ii) Time to first analgesia | ||
| (iii) Pain (VAS) scores | ||||
|
| ||||
| Mireskandari et al., 2015, Iran | 50 | General | (i) IV magnesium sulphate bolus (25) | (i) Total 24 hr PCA consumption (morphine) |
| (i) Thiopental 4 mg/kg | (ii) Normal saline control (25) | (ii) Pain (VAS) score | ||
| (ii) Fentanyl 1 μg/kg and midazolam 1 mg at delivery | ||||
|
| ||||
| Paech et al., 2006, Australia | 120 | Spinal-epidural | (i) IV magnesium sulphate bolus and 24 hr infusion (42). High dose: 50 mg/kg and 2 g/hr | (i) Total analgesia consumption (meperidine) |
| (i) Bupivacaine 0.5% | (ii) IV magnesium sulphate bolus and 24 hr infusion (38). Low dose: 25 mg/kg and 2 g/hr | (ii) Time to first analgesia | ||
| (ii) Fentanyl 15 μg | (iii) Normal saline control (40) | (iii) Pain (VAS) score | ||
|
| ||||
| Rezae et al., 2014, Iran | 70 | General | (i) Magnesium sulphate 50 mg/kg in 100 mL NS bolus (35) | (i) Total 24 hr analgesia consumption (morphine) |
| (i) Thiopental 6 mg/kg | ||||
| (ii) Fentanyl 2 μg/kg | (ii) Normal saline control (35) | (ii) Pain (VAS) score | ||
| (iii) Morphine 0.15 mg/kg after delivery | ||||
|
| ||||
| 530 | Receiving magnesium (260) | |||
IV = intravenous, hr = hours, VAS = visual analogue scale, PCA = patient controlled analgesia.