Table 2.
Regions | SNP | Patients n (%) | Controls n (%) | χ 2 | p values |
---|---|---|---|---|---|
Exon 2 | rs2228570 (FokI) | ||||
Genotype | |||||
CC | 84 (82.4%) | 0 (0.0%) | 182.95 | 0.0016∗ | |
CT | 13 (12.7%) | 0 (0.0%) | |||
TT | 5 (4.9%) | 100 (100%) | |||
Allele | |||||
C | 181 (88.7%) | 0 (0%) | 321.48 | 0.0015∗ | |
T | 23 (11.3%) | 200 (100%) | |||
| |||||
Intron 8 | rs7975232 (ApaI) | ||||
Genotype | |||||
GG | 33 (32.4%) | 86 (86.0%) | 64.34 | 0.014∗ | |
GT | 26 (25.5%) | 0 (0.0%) | |||
TT | 43 (42.2%) | 14 (14.0%) | |||
Allele | |||||
G | 92 (45.1%) | 172 (86%) | 74.61 | 0.015∗ | |
T | 112 (54.9%) | 28 (14%) | |||
| |||||
Exon 9 | rs731236 (TaqI) | ||||
Genotype | |||||
CC | 204 (100%) | 200 (100%) | 1.01 | 0.310 | |
Allele | |||||
C | 204 (100%) | 200 (100%) | 1.01 | 0.496 | |
| |||||
Intron 8 | KT280406 | ||||
Genotype | |||||
CG | 20 (4.1%) | 0 (0%) | 21.76 | 0.006∗ | |
GG | 184 (95.9%) | 30 (100%) | |||
Allele | |||||
C | 20 (9.8%) | 0 (0%) | 20.63 | 0.026∗ | |
G | 184 (90.2)% | 200 (100%) |
χ 2: chi-square test; ∗ represents significance at the 0.05 level.