Table 2. Reaction Yields and Biological Results for Compounds 8–17 when Screened against FGFR1.

^aPercent inhibition and IC₅₀ values are given as the mean ± SD of all data points.

^bReaction yields for Suzuki chemistry (SI-1.1).

^cNo difference in measured data points (N = 2).

^dNT = not tested.

^eLow yield explained by propensity of 2/4-hydroxyphenylboronic acids undergoing rapid protodeboronation.¹⁹