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. 2017 Nov 20;8(12):1320–1325. doi: 10.1021/acsmedchemlett.7b00404

Table 1. SAR of 5,6-Fused Ring Systems.

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a

Mean value determined from four replicates. Standard deviations are reported in the Supporting Information.

b

The concentration showing 50% increase in EPO release from Hep3B cells relative to the positive control. See the Supporting Information for assay details.

c

Apparent permeability coefficient.

d

HCl salt.

e

Value reported in ref (15).

f

Value reported in ref (16).