Table 1. SAR of 5,6-Fused Ring Systems.
Mean value determined from four replicates. Standard deviations are reported in the Supporting Information.
The concentration showing 50% increase in EPO release from Hep3B cells relative to the positive control. See the Supporting Information for assay details.
Apparent permeability coefficient.
HCl salt.
Value reported in ref (15).
Value reported in ref (16).