Biomarker expression patterns in HBV-infected and control HUHEP mice. Plasma from control (n=4) and HBV-infected (n=10) mice at the time of sacrifice (20 ±2 wpi) was analyzed by multiplex assay for human cytokines. IL-1b, IL-2, IL-2R, IL-4, IL-5, IL-6, IL-10, IL-12, IL-13, IL-15, IL-17, CCL2, CCL3, CCL5, GM-CSF, IFN-γ, and TNF-α were not detected. Dotted lines indicate the lower limit of quantification for each assay.