Table 1. Tomographic and visual acuity changes from baseline and 1, 3, 6, 12 and 18mo follow-up.
| Variables | Pre-treatment (95% CI) |
Post-treatment 1mo (P)a
(95% CI) |
Post-treatment 3mo (P)a
(95% CI) |
Post-treatment 6mo (P)a
(95% CI) |
Post-treatment 12mo (P)a
(95% CI) |
Post-treatment 18mo (P)a
(95% CI) |
| Kmin | 50.75±6.09 | 50.37±5.49 (0.08) | 50.65±6.02 (0.29) | 49.94±5.50 (0.13) | 49.78±5.23 (0.08) | 50.37±5.83 (0.06) |
| (48.12-53.39) | (47.99-52.74) | (48.04-53.25) | (47.57-52.32) | (47.52-52.04) | (47.85-52.89) | |
| Kmax | 57.34±6.65 | 56.12±6.05 (0.002) | 56.22±6.05 (0.001) | 56.39±6.01 (0.02) | 56.02±6.01 (<0.001) | 55.65±5.59 (<0.001) |
| (54.47-60.22) | (53.50-58.73) | (53.60-58.83) | (53.79-58.98) | (53.4-58.62) | (53.23-58.06) | |
| Km | 54.00±6.18 | 53.20±5.80 (0.01) | 53.49±6.14 (0.009) | 52.92±5.70 (0.03) | 52.87±5.62 (0.02) | 53.06±5.88 (0.001) |
| (51.32-56.67) | (50.69-55.7) | (50.82-56.14) | (50.46-55.39) | (50.44-55.30) | (50.51-55.60) | |
| Pachymetry | 434.64±37.84 | 436.26±39.05 (0.74) | 434.09±40.12 (0.54) | 427.96±47.07 (0.14) | 432.52±42.29 (0.41) | 430.09±54.26 (0.30) |
| (427-440) | (430-443) | (428-440) | (422-434) | (426-439) | (424-436) | |
| UDVA | 0.92±0.45 | 0.80±0.43 (0.01) | 0.85±0.45 (0.09) | 0.83±0.38 (0.04) | 0.75±0.40 (0.001) | 0.71±0.41 (<0.001) |
| (0.86-0.98) | (0.74-0.86) | (0.79-0.91) | (0.76-0.89) | (0.69-0.81) | (0.65-0.77) | |
| CDVA | 0.27±0.30 | 0.55±0.42 (0.0003)b | 0.35±0.42 (0.89) | 0.23±0.25 (0.23) | 0.16±0.16 (0.029) | 0.17±0.17 (0.05) |
| (0.18-0.35) | (0.46-0.63) | (0.27-0.44) | (0.14-0.31) | (0.07-0.24) | (0.09-0.26) |
aP value vs baseline; 95%CI: 95% Confidence interval; n=23 at each follow-up visit; bSignificant worsening; n=23 at each follow-up visit.